The U. Food and Drug Administration today approved Vyleesi bremelanotide to treat acquired, generalized hypoactive sexual desire disorder HSDD in premenopausal women. Joffe, M. HSDD is characterized by low sexual desire that causes marked distress or interpersonal difficulty and is not due to a co-existing medical or psychiatric condition, problems within the relationship or the effects of a medication or other drug substance. Acquired HSDD develops in a patient who previously experienced no problems with sexual desire. Vyleesi activates melanocortin receptors, but the mechanism by which it improves sexual desire and related distress is unknown. Patients inject Vyleesi under the skin of the abdomen or thigh at least 45 minutes before anticipated sexual activity and may decide the optimal time to use Vyleesi based on how they experience the duration of benefit and any side effects, such as nausea. Patients should not use more than one dose within 24 hours or more than eight doses per month.
What are the symptoms of HSDD?
Hypoactive sexual desire disorder HSDD is a troublesome condition in which women lose interest in sex. Hormonal changes, medication side effects, and stress can all dampen sex drive. But these periods are usually temporary and libido returns. HSDD is chronic and causes great distress for both women and their partners. Her partner might become frustrated and worry about the fate of the relationship. Distress is an important criterion for diagnosing HSDD. Often, a combination of these factors is the real culprit behind HSDD. For women who are experiencing chronic low sex drive, seeing a doctor is a good starting point. A complete physical can reveal — or rule out — common medical causes of HSDD.
If so, you may be experiencing low libido, a lack of desire for sexual intimacy in any form. Desire is the first part of the sexual response cycle , followed by arousal excitement , orgasm , and resolution the body returns to normal functioning. Men are having less sex than in the past, and some research suggests they are feeling less desire as well. A study published in the May issue of The Journal of Sexual Medicine found that the proportion of men reporting sexual activity within the past four weeks decreased from 81 percent in to 73 percent in , while lack of sexual desire increased from 8 to 13 percent. While low sex drive is not a concern in and of itself barring underlying physical illness , it can cause personal distress or lead to relationship issues for people whose partners want more sex. Men and women may lack sexual desire because of issues in three separate and competing areas, says Kimberly Resnick Anderson , a sex therapist and assistant professor of psychiatry at UCLA's David Geffen School of Medicine. Reclaiming desire can be a complex process.
But when a woman has a low libido or low sexual desire and is bothered by this lack of interest in sex, she may have a condition called hypoactive sexual desire disorder HSDD. This distress is an important component. After all, some women with what is considered a low libido may not have any distress or problems with a partner as a result. HSDD is treatable and can be manageable, so the first step if you are concerned about a lack of interest in sex is to talk to a healthcare provider to see what options are available. The first four questions are:. Medications may be evaluated as contributing factors, and underlying medical conditions may be addressed. One treatment involves taking a once-daily pill while the other is a self-administered shot taken as needed.